Calorimetric Detection of Thermal Transitions

How unfolding's extra heat requirement, measured directly rather than inferred from an indirect signal, gives a physically direct readout of a thermal transition.

References

• Privalov, P.L. "Scanning Microcalorimetry of Biological Macromolecules." Annual Review of Biophysics and Bioengineering 7 (1978): 523–535.