Cell-Mediated Cytotoxicity

How an immune effector cell recognizes and actively kills a target cell, and why that killing can be captured as a measurable release signal.

References

• Brunner, K.T., Mauel, J., Cerottini, J.C., Chapuis, B. "Quantitative Assay of the Lytic Action of Immune Lymphoid Cells on 51-Cr-Labelled Allogeneic Target Cells In Vitro." Immunology 14, no. 2 (1968): 181–196.