Correlative Light-Electron Microscopy (CLEM)

Correlates a fluorescently identified region with electron-microscopy ultrastructure, using fiducials and registration to relocate the same region across imaging modalities.

References

• De Rosier, D.J., Klug, A. "Reconstruction of Three Dimensional Structures." Nature 217, no. 5124 (1968): 130–134.