Complement Consumption as an Antibody-Antigen Readout
How a third-party reagent that's irreversibly used up specifically at antibody-antigen complexes lets its remaining, unconsumed amount indirectly reveal whether that reaction occurred.
References
- Müller-Eberhard, H.J., Schreiber, R.D. "Molecular Biology of Complement." Annual Review of Immunology 3 (1985): 645–682.