Differential Scanning Calorimetry (DSC)
Measures a molecule's thermal stability directly by tracking the heat absorbed as it unfolds during a controlled temperature ramp.
References
- Privalov, P.L., Khechinashvili, N.N. "A Thermodynamic Study of the Structure and Stability of Mononucleotides." Journal of Molecular Biology 86, no. 3 (1974): 665–684.