Electrophoretic Mobility Shift Assay (EMSA)

Detects protein-DNA binding by observing that a DNA fragment migrates more slowly through a gel once a protein is bound to it.

References

• Fried, M., Crothers, D.M. "Equilibria and Kinetics of Lac Repressor-Operator Interactions." Journal of Molecular Biology 181, no. 1 (1985): 41–62.