Salt-Modulated Hydrophobic Interaction

How a high salt concentration strengthens a protein's hydrophobic binding to a resin, letting a falling salt gradient release proteins gently in order of their surface hydrophobicity.

References

• Er-el, Z., Zaidenzaig, Y., Shaltiel, S. "Hydrocarbon-Coated Sepharoses. Use in the Purification of Glycogen Phosphorylase." Biochemical and Biophysical Research Communications 49, no. 2 (1972): 383–390.