Identifying Which Genes Drive a Phenotype, Genome-Wide

A cellular phenotype needs to be traced back to specific responsible genes, without needing to test thousands of candidate genes one at a time.

References

• Subramanian, A., Tamayo, P., Mootha, V.K., et al. "Gene Set Enrichment Analysis." Proceedings of the National Academy of Sciences 102, no. 43 (2005): 15545–15550.