Selective Lipid Removal as a Route to Optical Transparency

How reducing refractive-index heterogeneity, commonly by removing lipids, can render tissue optically transparent, with the degree of molecular loss and distortion depending on the specific clearing protocol used.

References

• Ponder, B., Richards, F.M. "Molecular Dynamics Simulations of Lipid Membranes." Current Opinion in Structural Biology 6, no. 4 (1996): 520–528.