Mass Spectrometry
Measures the mass-to-charge ratios of gas-phase ions; intact-ion mass constrains molecular mass, while controlled fragmentation and reference data can support molecular identification and structural inference.
References
- Fenn, J.B., Mann, M., Meng, C.K., Wong, S.F., Whitehouse, C.M. "Electrospray Ionization for Mass Spectrometry of Large Biomolecules." Science 246, no. 4926 (1989): 64–71.