Native Ion Mobility Mass Spectrometry
Adds a shape-based separation step to native mass spectrometry, revealing not just an intact complex's mass and composition but its overall conformation as well.
References
- Benesch, J.L.P., Ruotolo, B.T., Robinson, C.V. "Mass Spectrometry: Come of Age for Structural and Dynamical Biology." Current Opinion in Structural Biology 23, no. 6 (2013): 845–853.