Pooled CRISPR Screening

Tests thousands of genes for their role in a phenotype at once, by delivering a whole library of guide RNAs into a cell population and reading out which guides enrich or deplete afterward.

References

• Shalem, O., Sanjana, N.E., Hartenian, E., et al. "Genome-Scale CRISPR-Cas9." Science 343, no. 6166 (2014): 84–87.