Profiling Far More Markers Per Cell Than Fluorescence Allows

A cell population needs to be characterized across dozens of markers simultaneously on the very same individual cells, beyond what fluorescence-based detection can distinguish at once.

References

• Bodenmiller, B., Zunder, E.R., Finck, R., et al. "Multiplexed Mass Cytometry." Nature Biotechnology 30, no. 9 (2012): 858–867.