Quantifying DNA Damage on a Cell-by-Cell Basis

DNA strand breakage needs to be quantified for individual cells separately, revealing heterogeneity a single averaged bulk measurement across a whole population would completely obscure.

References

• Singh, N.P., McCoy, M.T., Tice, R.R., Schneider, E.L. "Comet Assay." Experimental Cell Research 175, no. 1 (1988): 184–191.