Ribosome Footprinting

How the specific stretch of mRNA a ribosome physically covers survives broad enzymatic digestion, letting active translation be read directly from what's protected.

References

• Ingolia, N.T., Ghaemmaghami, S., Newman, J.R., Weissman, J.S. "Genome-Wide Analysis of Translation." Science 324, no. 5924 (2009): 218–223.