Sequence-to-Structure Inference

How correlated sequence variation across homologs can provide structural constraints that improve protein-structure inference.

References

• Jumper, J., Evans, R., Pritzel, A., Green, T., Figurnov, M., Ronneberger, O., et al. "Highly Accurate Protein Structure Prediction with AlphaFold." Nature 596, no. 7873 (2021): 583–589.