DNA Fragment Size as a Migration-Based Damage Readout

Why intact genomic DNA barely moves under an electric field while damage-fragmented DNA streams outward, converting strand breaks into a directly visible, measurable migration pattern.

References

• Singh, N.P., McCoy, M.T., Tice, R.R., Schneider, E.L. "Comet Assay." Experimental Cell Research 175, no. 1 (1988): 184–191.