Stably Delivering a Genetic Construct Into Mammalian Cells
A genetic construct needs to be delivered into mammalian cells, including non-dividing ones, so it becomes a permanent, heritable part of the cell rather than a transient, gradually lost addition.
References
- Friedmann, T., Roblin, R. "Gene Therapy for Human Genetic Disease." Science 175, no. 4025 (1972): 949–955.