TALEN Gene Editing

Cuts one specific genomic sequence by using a custom-built DNA-binding protein, rather than a guide RNA, to direct a cutting enzyme to the target site.

References

• Bogdanove, A.J., Voytas, D.F. "TALEs: Customizable Proteins for DNA Targeting." Science 333, no. 6051 (2011): 1843–1846.