Antibody-Tethered Enzyme Action at a Bound Protein's Location

Why physically anchoring a cutting or tagging enzyme to an antibody bound at a specific protein lets that enzyme act only in the immediate vicinity of that protein's genomic locations.

References

• Greskovich, P.A., Dignam, J.D. "Nucleosome Assembly." Methods in Enzymology 170 (1989): 536–545.