Antigen-Specific T Cell (Tetramer) Staining

Identifies and counts T cells whose receptors bind a specific peptide–MHC complex using fluorescent MHC multimers.

References

• Altman, J.D., Moss, P.A., Goulder, P.J., Barouch, D.H., McHeyzer-Williams, M.G., Bell, J.I., McMichael, A.J., Davis, M.M. "Phenotypic Analysis of Antigen-Specific T Lymphocytes." Science 274, no. 5284 (1996): 94–96.