Transposase-Based Chromatin Accessibility Tagging

How adapter-loaded Tn5 preferentially tags accessible chromatin, producing an accessibility proxy after accounting for sequence and structural bias.

References

• Buenrostro, J.D., Giresi, P.G., Zaba, L.C., et al. "Transposition of Native Chromatin." Nature Methods 10, no. 12 (2013): 1213–1218.